N. Acharya

Induced electric fields inhibit breast cancer growth and metastasis by modulating the immune tumor microenvironment

This study shows that induced electric fields reduce breast cancer growth and metastasis by enhancing anti-tumor immunity and modulating the tumor microenvironment in mice.

The distribution of Apis laboriosa revisited: range extensions and biogeographic affinities

This paper revises the distribution of Apis laboriosa, extending its range and discussing biogeographic affinities and new localities.

A chemically-induced attenuated strain of Candida albicans generates robust protective immune responses and prevents systemic candidiasis development

The paper attenuates Candida albicans using EDTA to create a live vaccine candidate that induces protective immunity and prevents systemic candidiasis in mice.

Trem2 Promotes Foamy Macrophage Lipid Uptake and Survival in Atherosclerosis

This study identifies Trem2 as a regulator of foamy macrophage differentiation and atherosclerotic plaque growth, showing its role in lipid uptake and cell survival.

Commensal fungi Candida albicans modulates dietary high-fat induced alterations in metabolism, immunity, and gut microbiota

This study shows that dietary Candida albicans modulates gut microbiota, metabolism, and immunity, preventing high-fat diet-induced weight gain and inflammation in mice.

Molecular basis for substrate recruitment to the PRMT5 methylosome

The paper identifies a conserved peptide sequence in PRMT5 substrate adaptors that mediates their interaction with PRMT5 and shows its necessity for methylation of substrates like spliceosome, histones, and ribosome complexes.

Identification of PCNA interacting protein motifs in human DNA polymerase delta

The paper identifies a non-canonical PIP box in human DNA polymerase delta p125 that binds PCNA, contributing to its processive replication function.

An endogenous glucocorticoid-cytokine signaling circuit promotes CD8+ T cell dysfunction in the tumor microenvironment

This study identifies a glucocorticoid-cytokine signaling circuit in the tumor microenvironment that promotes CD8+ T cell dysfunction and correlates with poor response to checkpoint blockade in melanoma.