Dynamic culture of cerebral organoids using a pillar/perfusion plate for the assessment of developmental neurotoxicity
P. Acharya, S. Shrestha, P. Joshi, N. Y. Choi, V. K. R. Lekkala, S.-Y. Kang, G. Ni, M.-Y. Lee
This study evaluates developmental neurotoxicity using dynamic cerebral organoid cultures in a pillar/perfusion plate, showing methylmercury induces changes in morphology and gene expression under dynamic conditions but not static ones.
bioRxiv · Mar 11, 2024Bioengineering