Author

S.-Y. Kang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 5 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:drug response / drug discovery· 5 Organism:human· 5 Assay:organoid / primary culture· 5 Research Focus:cell type annotation· 3 Research Focus:clustering· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

M.-Y. Lee· 5 shared P. Acharya· 5 shared S. Shrestha· 5 shared P. Joshi· 4 shared V. K. R. Lekkala· 4 shared J. Liu· 3 shared Y. Yang· 3 shared M. G. Vanga· 2 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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5 shared papersBioengineering

M.-Y. Lee

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Regenerative human liver organoids (HLOs) in a pillar/perfusion plate for hepatotoxicity assays

S. Shrestha, P. Acharya, S.-Y. Kang, M. G. Vanga, V. K. R. Lekkala, J. Liu, Y. Yang, P. Joshi, M.-Y. Lee

This paper develops a bioprinted liver organoid system for high-throughput hepatotoxicity assays, showing improved maturity, reproducibility, and regenerative capacity after drug exposure.

bioRxiv · Mar 25, 2024 · PreprintBioengineering

Dynamic culture of cerebral organoids using a pillar/perfusion plate for the assessment of developmental neurotoxicity

P. Acharya, S. Shrestha, P. Joshi, N. Y. Choi, V. K. R. Lekkala, S.-Y. Kang, G. Ni, M.-Y. Lee

This study evaluates developmental neurotoxicity using dynamic cerebral organoid cultures in a pillar/perfusion plate, showing methylmercury induces changes in morphology and gene expression under dynamic conditions but not static ones.

bioRxiv · Mar 11, 2024Bioengineering

Reproducible generation of human liver organoids (HLOs) on a pillar plate platform via microarray 3D bioprinting

S. Shrestha, V. K. R. Lekkala, P. Acharya, S.-Y. Kang, M. G. Vanga, M.-Y. Lee

This paper develops a microarray 3D bioprinting method to generate human liver organoids on a pillar plate, enabling high-throughput, reproducible hepatotoxicity assays with improved efficiency and function.

bioRxiv · Mar 11, 2024Bioengineering

A Pillar and Perfusion Plate Platform for Robust Human Organoid Culture and Analysis

S.-Y. Kang, M. Kimura, S. Shrestha, P. Lewis, S. Lee, Y. Cai, P. Joshi, P. Acharya, J. Liu, Y. Yang, J. G. Sanchez, S. Ayyagari, E. Alsberg, J. Wells, T. Takebe, M.-Y. Lee

This paper introduces a microarray 3D bioprinting platform with pillar and perfusion plates for high-throughput human organoid culture and analysis.

bioRxiv · Mar 11, 2023Bioengineering

A pillar/perfusion plate enhances cell growth, reproducibility, throughput, and user friendliness in dynamic 3D cell culture

V. K. R. Lekkala, S.-Y. Kang, J. Liu, S. Shrestha, P. Acharya, P. Joshi, M. Zolfaghar, M. Lee, P. Jamdagneya, S. Pagnis, A. Kundi, S. Kabbur, U. T. Kim, Y. Yang, M.-Y. Lee

The paper introduces a pillar/perfusion plate for dynamic 3D cell culture, improving growth, reproducibility, throughput, and user friendliness compared to static methods.

bioRxiv · Feb 16, 2023Bioengineering

Nanoengineered DNA origami with repurposed TOP1 inhibitors targeting myeloid cells for the mitigation of neuroinflammation

K. Zhu, Y. Wang, H. Sarlus, K. Geng, E. Nutma, J. Sun, S.-Y. Kang, C. Bay, J. Han, H. Lund, S. Amor, J. Wang, X.-m. Zhang, C. Kutter, A. Ortlieb, , R. Harris

The paper identifies TOP1 inhibitors as therapeutic agents for neuroinflammation and develops a DNA origami nanosystem for targeted delivery to myeloid cells.

bioRxiv · Oct 4, 2021Immunology