Author

Y. H. Xia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

E. Panzhinskiy· 2 shared J. D. Johnson· 2 shared S. Skovso· 2 shared X. Hu· 2 shared A. M. Y. Zhang· 1 shared C. Chao· 1 shared C. Ellis· 1 shared C. H. Borchers· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

E. Panzhinskiy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dynamic Ins2 gene activity defines β-cell maturity states

C. M. J. Chu, H. Modi, S. Skovso, C. Ellis, N. A. J. Krentz, Y. B. Zhao, H. Cen, N. Noursadeghi, E. Panzhinskiy, X. Hu, D. A. Dionne, Y. h. Xia, S. Xuan, M. O. Huising, T. J. Kieffer, , J. Johnson

This study shows that β-cell heterogeneity in insulin production is due to dynamic Ins2 gene activity states, with high activity linked to maturity and reduced viability.

bioRxiv · Jul 18, 2022Cell Biology

Sex differences in islet stress responses support female beta cell resilience

G. P. Brownrigg, Y. H. Xia, C. M. Jamie Chu, S. Wang, C. Chao, J. A. Zhang, S. Skovso, E. Panzhinskiy, X. Hu, J. D. Johnson, E. J. Rideout

This study identifies sex differences in beta cell stress responses, showing female beta cells are more resilient to ER stress in both human and mouse models.

bioRxiv · May 10, 2022 · PreprintCell Biology

Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation

A. M. Y. Zhang, Y. H. Xia, J. S. H. Lin, K. H. Chu, W. C. K. Wang, T. J. J. Ruiter, J. C. C. Yang, N. Chen, J. Chhuor, S. Patil, H. H. Cen, E. Rideout, V. R. Richard, D. F. Schaeffer, R. P. Zahedi, , J. Kopp

bioRxiv · May 6, 2022Cancer Biology