Author

J. A. Zhang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

E. Panzhinskiy· 2 shared J. D. Johnson· 2 shared S. Skovso· 2 shared A. G. Edwards· 1 shared A. G. Gordon· 1 shared C. Chao· 1 shared C. M. J. Chu· 1 shared C. M. Jamie Chu· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPhysiology

E. Panzhinskiy

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Pharmacological or genetic inhibition of Scn9a protects human and mouse beta cells while dampening insulin secretion in type 1 diabetes

P. Overby, A. G. Gordon, X.-Q. Dai, N. S. Nahirney, S. Provenzano, W. G. Sun, Y. Xia, J. A. Zhang, E. Panzhinskiy, C. M. J. Chu, H. H. Cen, S. Skovso, J. Kolic, A. G. Edwards, P. E. Macdonald, J. D. Johnson

This study shows that inhibiting Scn9a protects beta cells in type 1 diabetes by reducing excitability and improving survival, while also dampening insulin secretion.

bioRxiv · Jun 11, 2023 · PreprintPhysiology

Sex differences in islet stress responses support female beta cell resilience

G. P. Brownrigg, Y. H. Xia, C. M. Jamie Chu, S. Wang, C. Chao, J. A. Zhang, S. Skovso, E. Panzhinskiy, X. Hu, J. D. Johnson, E. J. Rideout

This study identifies sex differences in beta cell stress responses, showing female beta cells are more resilient to ER stress in both human and mouse models.

bioRxiv · May 10, 2022 · PreprintCell Biology