G. Pereira

Balancing the length of distal tip is key for stability and signalling function of primary cilia

The paper identifies Septins as regulators of distal cilia segment growth and shows their role in controlling cilia length and SHH signaling.

The Food Additive Xanthan Gum Drives Adaptation of the Human Gut Microbiota

This study shows that xanthan gum, a common food additive, promotes the adaptation of the human gut microbiota by enabling a novel degradation pathway in an uncultured Ruminococcaceae bacterium and facilitating cross-feeding by Bacteroides species.

SWR1 Chromatin Remodeling Complex Prevents Mitotic Slippage during Spindle Position Checkpoint Arrest

This study identifies the SWR1 chromatin-remodeling complex as essential for maintaining prolonged spindle position checkpoint (SPOC) arrest, preventing mitotic slippage in budding yeast.

CRISPR-Cas12a-assisted PCR tagging of mammalian genes

This paper describes a method for efficient endogenous gene tagging in mammalian cells using CRISPR-Cas12a and PCR cassettes, achieving up to 60% tagging efficiency with selection.

Analysis of LRRC45 indicates cooperative functions of distal appendages at early steps of ciliogenesis

This study identifies LRRC45's role in ciliogenesis by showing it recruits FBF1 to the mother centriole and promotes cilia biogenesis in CP110-uncapped centrioles.