Diethylcarbamazine elicits Ca2+ signals through TRP-2 channels that are potentiated by emodepside in Brugia malayi muscles
P. D. Williams, S. S. Kashyap, A. Robertson, R. J. Martin
This study shows diethylcarbamazine activates TRP-2 channels in Brugia malayi muscles, increasing Ca2+ entry, which is enhanced by emodepside's effect on SLO-1 channels.
bioRxiv · Apr 10, 2023 · PreprintPharmacology & Toxicology