IFNgamma-dependent remodelling of the myeloid landscape underlies control of IFNgamma-insensitive tumours
V. W. C. Lau, G. Mead, J. M. Mazet, A. Krishnan, E. W. Roberts, G. Prota, U. Gileadi, V. Cerundolo, A. Gerard
The paper shows that IFN-gamma-insensitive tumours can still be controlled by immune responses, with IFN-gamma driving myeloid cell remodelling that enhances anti-tumour immunity.
bioRxiv · Mar 25, 2024Immunology