Author

U. Gileadi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:CITE-seq· 1

Frequent Co-Authors

V. Cerundolo· 4 shared G. Prota· 2 shared J.-L. Chen· 2 shared A. B. van Spriel· 1 shared A. Bartolo-Ibars· 1 shared A. Gerard· 1 shared A. Krishnan· 1 shared A. Simmons· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersImmunology

V. Cerundolo

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Author profile →

4 papers

Recent·Most cited

IFNgamma-dependent remodelling of the myeloid landscape underlies control of IFNgamma-insensitive tumours

V. W. C. Lau, G. Mead, J. M. Mazet, A. Krishnan, E. W. Roberts, G. Prota, U. Gileadi, V. Cerundolo, A. Gerard

The paper shows that IFN-gamma-insensitive tumours can still be controlled by immune responses, with IFN-gamma driving myeloid cell remodelling that enhances anti-tumour immunity.

bioRxiv · Mar 25, 2024Immunology

Immunofilaments Provide a Nanoscale Platform for In Vivo T Cell Expansion and Cancer Immunotherapy

L. Weiss, J. Weiden, Y. Dölen, E. Grad, E. A. W. van Dinther, M. Schluck, L. J. Eggermont, G. van Mierlo, U. Gileadi, A. Bartolo-Ibars, R. Raave, M. A. J. Gorris, K. Verrijp, M. Valente, B. Deplancke, , R. Hammink

This paper introduces immunofilaments that expand T cells in vivo, showing efficacy against melanoma when combined with immune checkpoint blockade.

bioRxiv · Oct 14, 2022Immunology

Semaphorin 3A induces cytoskeletal paralysis in tumor-specific CD8+ T cells

M. B. Barnkob, Y. S. Michaels, V. Andre, P. S. Macklin, U. Gileadi, S. Valvo, M. Rei, C. Kulicke, J.-L. Chen, V. Jain, V. Woodcock, H. Colin-York, A. V. Hadjinicolaou, Y. Kong, V. Mayya, , V. Cerundolo

This study shows Sema3A inhibits tumor-specific CD8+ T cell function by inducing cytoskeletal paralysis via NRP1 in the tumor microenvironment.

bioRxiv · Nov 20, 2019Immunology

NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-presentation and CD8 T Cell Responses

D. Corridoni, S. Shiraishi, T. Chapman, T. Steevels, D. Muraro, M.-L. Thezenas, G. Prota, J.-L. Chen, U. Gileadi, N. Ternette, V. Cerundolo, A. Simmons

This study identifies TBK1 and PI31 as key mediators of NOD2 and TLR2 signaling in dendritic cells, enhancing cross-presentation and CD8+ T cell responses against bacterial pathogens.

bioRxiv · Mar 8, 2019Immunology