G. R. Rojas

Differential processing of delay versus uncertainty in male but not female 16p11.2 hemideletion mice

This study shows that male 16p11.2 hemideletion mice show distinct decision-making patterns under delay and uncertainty compared to wildtype males, while females show no such differences.

Endosomal removal and disposal of dysfunctional, immunostimulatory mitochondrial DNA

The paper investigates how dysfunctional mitochondrial DNA is removed via an endosomal pathway, showing that defects in mtDNA replication and segregation trigger a fission checkpoint leading to immune activation and eventual disposal through RAB7-containing endosomes.

Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT

This study links TOP1MT deficiency and the P193L variant to mtDNA release and cGAS-STING activation, contributing to autoimmune disease susceptibility.

Sequential delay and probability discounting tasks in mice reveal anchoring effects partially attributable to decision noise

This study shows that anchoring effects in mice during delay and probability discounting tasks are more likely due to decision noise than persistent value changes, with females showing less anchoring than males.