Author

P. West

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Goldstein· 1 shared A. K. Coleman· 1 shared A. Khan· 1 shared A. Niamir· 1 shared A. Voskamp· 1 shared A. Walsh· 1 shared B. Bertzky· 1 shared B. K. Chung· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperEcology

A. Goldstein

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Machine learning prediction of cancer cell metabolism from autofluorescence lifetime images

L. Hu, N. Wang, J. Bryant, L. Liu, L. Xie, P. West, A. Walsh

This paper uses machine learning on autofluorescence lifetime images to predict metabolic pathway usage in cancer cells, achieving 95% accuracy in distinguishing glycolytic and oxidative metabolism.

bioRxiv · Dec 16, 2022 · PreprintBioengineering

Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT

I. Al Khatib, J. Deng, Y. Lei, S. Torres-Odio, G. R. Rojas, L. E. Newman, B. K. Chung, S. A. Symes, H. Zhang, S.-y. N. Huang, Y. Pommier, A. Khan, G. S. Shadel, P. West, W. Gibson, T. Shutt

This study links TOP1MT deficiency and the P193L variant to mtDNA release and cGAS-STING activation, contributing to autoimmune disease susceptibility.

bioRxiv · Mar 8, 2022Cell Biology

Utilizing multi-objective decision support tools for protected area selection

A. Voskamp, S. A. Fritz, V. Koecke, M. Biber, T. Nogueira-Brockmeyer, B. Bertzky, M. Forrest, A. Goldstein, S. Henderson, T. Hickler, C. Hof, T. Kastner, S. Lang, P. Manning, M. B. Mascia, , K. Boehning-Gaese

This paper presents a global decision support tool for selecting protected areas by balancing multiple conservation objectives and highlighting trade-offs among them.

bioRxiv · Feb 15, 2022Ecology

Mitochondrial dysfunction promotes alternative gasdermin D-mediated inflammatory cell death and susceptibility to infection

C. G. Weindel, X. Zhao, E. Martinez, S. L. Bell, K. J. Vail, A. K. Coleman, J. J. VanPortfliet, B. Zhao, C. Mabry, P. Li, P. West, J. Karpac, K. L. Patrick, R. O. Watson

This study shows that mitochondrial dysfunction caused by Lrrk2G2019S promotes non-pyroptotic cell death via GSDMD and increases susceptibility to infection.

bioRxiv · Nov 18, 2021 · PreprintImmunology