G. Russo

The genomic trajectory of ovarian high grade serous carcinoma is determined in STIC lesions

This study shows that high ploidy and whole genome duplication in ovarian high-grade serous carcinoma originate in STIC lesions, indicating early determination of the tumor's genomic trajectory.

Septin-associated PIPKIγ splice variants drive centralspindlin association with the midbody via PI(4,5)P2

This study identifies septin-associated PIPKIγ splice variants as essential for midbody organization by generating PI(4,5)P2 required for centralspindlin recruitment and septin-microtubule association.

Reorganization of Septin structures regulates early myogenesis

This study shows Septin9 regulates myoblast differentiation by reorganizing cytoskeletal structures during early myogenesis.

Metatranscriptome of infected root canals in teeth with apical periodontitis

This study uses metatranscriptomics to analyze the microbial composition and gene expression in root canals with apical periodontitis, revealing dominant phyla, virulence factors, and antimicrobial resistance.

Competition-cooperation in the chemoautotrophic ecosystem of Movile Cave - first metagenomic approach on sediments

This study uses metagenomics to analyze sediments in Movile Cave, revealing microbial diversity, metabolic potential, and competition-cooperation dynamics beyond sulfidic thermal waters.

A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients by phage display is binding to the ACE2-RBD interface and is tolerant to most known recently emerging RBD mutations

The paper describes the selection of a SARS-CoV-2 neutralizing antibody from COVID-19 patients using phage display, showing it binds the ACE2-RBD interface and remains effective against emerging RBD mutations.

SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface

The paper identifies potent SARS-CoV-2 neutralizing antibodies from pre-pandemic human donors that bind the RBD-ACE2 interface, showing high neutralization efficacy in vitro.

FGFR2 fusion protein-driven mouse models of intrahepatic cholangiocarcinoma unveil a necessary role for Erk signaling

This paper develops FGFR2 fusion protein-driven mouse models of intrahepatic cholangiocarcinoma and shows that Erk signaling is essential for tumor growth, with double blockade of FF-Ras-Erk pathways improving therapeutic efficacy.

Cell Cycle Constraints and Environmental Control of Local DNA Hypomethylation in Alpha-Proteobacteria

The paper identifies how cell cycle regulators and environmental factors influence DNA hypomethylation patterns in alpha-proteobacteria.