F. Heyd

AFC kinases regulate warm temperature-responsive growth in Arabidopsis

This study shows that AFC kinases in Arabidopsis regulate warm temperature-responsive growth by controlling splicing patterns and hypocotyl elongation through phosphorylation of SR proteins.

Comparison of the CDC2-like kinase family across eukaryotes highlights the functional conservation of these unique biological thermometers

This study compares CDC2-like kinases across eukaryotes, showing their evolutionary conservation, thermo-sensitive properties, and role in alternative splicing regulation.

Septin-associated PIPKIγ splice variants drive centralspindlin association with the midbody via PI(4,5)P2

This study identifies septin-associated PIPKIγ splice variants as essential for midbody organization by generating PI(4,5)P2 required for centralspindlin recruitment and septin-microtubule association.

Identification of a link between splicing and endoplasmic reticulum proteostasis

This study identifies SNRPB as a regulator of ER export and links it to osteogenesis and CCMS through its effects on splicing and the UPR.

Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition

This study shows that inhibiting HDAC6 with Marbostat-100 reduces MYC levels and prevents lymphomagenesis in a mouse model of MYC-induced B-cell lymphoma.

A homozygous genome-edited Sept2-EGFP fibroblast cell line

The paper generates a homozygous genome-edited rat fibroblast cell line expressing Sept2-EGFP from both chromosomal loci and validates its proper function and localization.

Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway

The paper identifies over 200 alternative splicing events regulating protein transport across the secretory pathway using RNA-Seq and genetic perturbations.