Author

G. Sakoulas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:whole-genome sequencing· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

V. Nizet· 3 shared S. Uchiyama· 2 shared A. Flores· 1 shared A. M. Feist· 1 shared A. Riestra· 1 shared B. Aguilar· 1 shared B. O. Palsson· 1 shared B. Palsson· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersMicrobiology

V. Nizet

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Unrecognized Potent Activities of Colistin Against Clinically Important mcr+ Enterobacteriaceae Revealed in Synergy with Host Immunity

M. Kumaraswamy, A. Riestra, A. Flores, S. Uchiyama, S. Dahesh, G. Bondsater, V. Nilsson, M. Chang, H. Seo, G. Sakoulas, V. Nizet

This study reveals that colistin has previously unrecognized bactericidal activity against mcr-1+ Gram-negative bacteria in physiologic conditions and synergizes with host immunity.

bioRxiv · Mar 21, 2023Microbiology

Repurposed Drugs Block Toxin-Driven Platelet Clearance by the Hepatic Ashwell-Morell Receptor to Clear Staphylococcus aureus Bacteremia

J. Sun, S. Uchiyama, J. Olson, Y. Morodomi, I. Cornax, N. Ando, Y. Kohno, M. M. T. Kyaw, B. Aguilar, N. M. Haste, S. Kanaji, T. Kanaji, W. E. Rose, G. Sakoulas, J. D. Marth, V. Nizet

Science Translational Medicine · Mar 24, 2021Peer-reviewedMicrobiology

Environmental conditions dictate differential evolution of vancomycin resistance in Staphylococcus aureus

H. Machado, Y. Seif, G. Sakoulas, C. A. Olson, R. Szubin, B. Palsson, V. Nizet, A. M. Feist

This study identifies media-specific mutational mechanisms of vancomycin resistance in S. aureus using adaptive laboratory evolution and sequencing.

bioRxiv · Jun 7, 2020Microbiology

The Staphylococcus aureus Two-Component System AgrAC Displays Four Distinct Genomic Arrangements That Delineate Genomic Virulence Factor Signatures

K. S. Choudhary, N. Mih, J. Monk, E. Kavvas, J. T. Yurkovich, G. Sakoulas, B. O. Palsson

The paper classifies S. aureus strains based on AgrAC TCS genomic arrangements, linking agr types to virulence factor presence and protein structural properties.

bioRxiv · Mar 6, 2018Microbiology