Author

W. E. Rose

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

A. B. Banta· 1 shared A. Bayer· 1 shared A. E. Rosato· 1 shared A. M. Bienvenida· 1 shared A. Taglialegna· 1 shared B. Aguilar· 1 shared C. I. Lew· 1 shared C. M. Grunenwald· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 5 mutual co-author links

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1 shared paperMicrobiology

A. B. Banta

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Essential Gene Phenotypes Reveal Antibiotic Mechanisms and Synergies in Acinetobacter baumannii

R. D. Ward, J. S. Tran, A. B. Banta, E. E. Bacon, W. E. Rose, J. M. Peters

This study uses CRISPRi to identify essential genes in A. baumannii and their interactions with antibiotics, revealing therapeutic targets and synergy mechanisms.

bioRxiv · Nov 9, 2022 · PreprintMicrobiology

PASTA kinase-dependent control of peptidoglycan synthesis via ReoM is required for cell wall stress responses, cytosolic survival, and virulence in Listeria monocytogenes

J. L. Kelliher, C. M. Grunenwald, R. R. Abrahams, M. E. Daanen, C. I. Lew, W. E. Rose, J.-D. Sauer

This study identifies ReoM as a phosphosubstrate of PrkA in Listeria monocytogenes, showing its role in peptidoglycan synthesis and virulence during cell wall stress.

bioRxiv · Aug 20, 2021Microbiology

Repurposed Drugs Block Toxin-Driven Platelet Clearance by the Hepatic Ashwell-Morell Receptor to Clear Staphylococcus aureus Bacteremia

J. Sun, S. Uchiyama, J. Olson, Y. Morodomi, I. Cornax, N. Ando, Y. Kohno, M. M. T. Kyaw, B. Aguilar, N. M. Haste, S. Kanaji, T. Kanaji, W. E. Rose, G. Sakoulas, J. D. Marth, V. Nizet

Science Translational Medicine · Mar 24, 2021Peer-reviewedMicrobiology

Ability of Bicarbonate Supplementation to Sensitize Selected Methicillin-Resistant Staphylococcus aureus (MRSA) Strains to β-Lactam Antibiotics in an Ex Vivo Simulated Endocardial Vegetation Model

W. E. Rose, A. M. Bienvenida, Y. Q. Xiong, H. F. Chambers, A. Bayer, S. C. Ersoy

This study shows that bicarbonate supplementation increases β-lactam susceptibility in certain MRSA strains in an ex vivo endocarditis model, but not in others.

bioRxiv · Oct 16, 2019Microbiology

Activity of Telavancin against S. aureus isolated from cystic fibrosis patients including those with decreased susceptibility to Ceftaroline

M. Roch, M. C. Varela, A. Taglialegna, W. E. Rose, A. E. Rosato

This study evaluates telavancin's activity against S. aureus from cystic fibrosis patients, finding it more effective than several other antibiotics with low resistance potential.

bioRxiv · May 10, 2018Microbiology