Author

G. Trynka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. Soskic· 1 shared C. G. C. Larminie· 1 shared D. F. Tough· 1 shared D. J. Smyth· 1 shared D. Wille· 1 shared E. C. Gamez· 1 shared E. So· 1 shared G. Donati· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

B. Soskic

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines

E. C. Gamez, B. Soskic, T. I. Roumeliotis, E. So, D. J. Smyth, M. Baldrighi, D. Wille, N. Nakic, J. Esparza-Gordillo, C. G. C. Larminie, P. G. Bronson, D. F. Tough, W. C. Rowan, J. S. Choudhary, G. Trynka

The paper uses single-cell RNA-seq and other methods to show that CD4+ T cells form an effectorness gradient, with cytokine responses varying along this continuum.

bioRxiv · Sep 4, 2019Immunology

Gene expression variability across cells and species shapes innate immunity

T. Hagai, X. Chen, R. J. Miragaia, T. Gomes, R. Rostom, N. Kunowska, V. Proserpio, G. Donati, L. Bossini-Castillo, G. Naamati, G. Emerton, G. Trynka, I. Kondova, M. Denis, S. A. Teichmann

The paper examines how gene expression variability across cells and species influences innate immune responses, finding that rapidly diverging genes show high variability while regulatory genes are conserved.

bioRxiv · Sep 24, 2017Evolutionary Biology