Author

G. W. Pearson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Nasir· 2 shared A. B. Jaykumar· 1 shared A. Lekan· 1 shared A. T. McIntosh· 1 shared A. T. Riegel· 1 shared B. Johnson· 1 shared C. Wichaidit· 1 shared D. J. Wilkins· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

A. Nasir

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Author profile →

3 papers

Recent·Most cited

Zebrafish xenografts to isolate unique human breast cancer metastatic cell populations

J. Xiao, J. R. McGill, A. Nasir, A. Lekan, B. Johnson, D. J. Wilkins, G. W. Pearson, K. Tanner, H. Goodarzi, E. Glasgow, R. Schlegel, S. Agarwal

This paper develops a zebrafish xenograft model to isolate and study human breast cancer metastatic cells, identifying genes and pathways involved in invasion.

bioRxiv · Dec 7, 2021Cancer Biology

WNK1 Enhances Migration and Invasion in Breast Cancer Models

A. B. Jaykumar, J. Jung, P. Parida, T. T. Dang, M. Grzemska, S. Earnest, C. Wichaidit, E. J. Goldsmith, G. W. Pearson, S. Malladi, M. H. Cobb

This study shows that inhibiting WNK1 reduces migration, invasion, and metastasis in breast cancer models.

bioRxiv · Mar 9, 2021Cancer Biology

The integration of Tgfβ and Egfr signaling programs confers the ability to lead heterogeneous collective invasion

A. Nasir, S. Camacho, A. T. McIntosh, G. T. Graham, R. Rahhal, M. E. Huysman, F. Alsharief, A. T. Riegel, G. W. Pearson

The paper identifies a Tgfβ-induced trailblazer population that integrates with Egfr signaling to promote collective invasion and shows this integration can be therapeutically targeted.

bioRxiv · Nov 14, 2020 · PreprintCancer Biology