Author

S. Earnest

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. Wichaidit· 3 shared M. H. Cobb· 3 shared A. Augustyn· 1 shared A. B. Jaykumar· 1 shared A. F. Gazdar· 1 shared A. M. Klein· 1 shared A. Martin-Vega· 1 shared A. S. Karra· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

C. Wichaidit

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers

A. Martin-Vega, S. Earnest, A. Augustyn, C. Wichaidit, A. F. Gazdar, L. Girard, M. Peyton, R. K. Kollipara, J. D. Minna, J. E. Johnson, M. H. Cobb

This study identifies the ASCL1-DUSP6-ERK1/2 axis as a mechanism promoting survival in neuroendocrine lung cancers, suggesting DUSP6 as a potential therapeutic target.

bioRxiv · Jun 15, 2023 · PreprintCancer Biology

WNK1 Enhances Migration and Invasion in Breast Cancer Models

A. B. Jaykumar, J. Jung, P. Parida, T. T. Dang, M. Grzemska, S. Earnest, C. Wichaidit, E. J. Goldsmith, G. W. Pearson, S. Malladi, M. H. Cobb

This study shows that inhibiting WNK1 reduces migration, invasion, and metastasis in breast cancer models.

bioRxiv · Mar 9, 2021Cancer Biology

ERK2 phosphorylates the epigenetic regulator CXXC-finger protein 1 (Cfp1)

A. S. Karra, A. M. Klein, S. Earnest, S. Stippec, C. Wichaidit, K. McGlynn, D. C. Trudgian, H. Mirzaei, M. H. Cobb

The paper identifies CFP1 as an ERK2 substrate involved in chromatin regulation and shows its role in modulating histone methylase activity through phosphorylation.

bioRxiv · Mar 8, 2019 · PreprintCell Biology