Psychiatric risk gene NT5C2 regulates protein translation in human neural progenitor cells
Rodrigo R. R. Duarte, Nathaniel D. Bachtel, Marie-Caroline Côtel, Sang Hyuck Lee, Sashika Selvackadunco, Iain A. Watson, Gary A. Hovsepian, Claire Troakes, Gerome D. Breen, Douglas F. Nixon, Robin M. Murray, Nicholas J. Bray, Ioannis Eleftherianos, Anthony Christopher Vernon, Timothy R. Powell, Deepak P. Srivastava
This study identifies NT5C2 as a psychiatric risk gene, showing its role in protein translation and AMPK signaling in neural progenitor cells and Drosophila melanogaster.
Biological Psychiatry · Mar 29, 2019Peer-reviewedNeuroscience