Author

Grace E. Kim

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Changfei Luan· 2 shared Jen Jen YehiD· 2 shared Alexander LiiD· 1 shared Andrew Victor BiankiniD· 1 shared Anna‐Marie FingeriD· 1 shared Atsushi Urano· 1 shared Audrey M. HendleyiD· 1 shared Bruce WangiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Changfei Luan

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2 papers

Recent·Most cited

PCSK9 dependent cholesterol acquisition and utilization underlies metastatic organ preference in pancreatic cancer.

Gilles Rademaker, Grace A. Hernandez, Sumena Dahal, Lisa Miller‐Phillips, Alexander Li, Changfei Luan, Longhui Qui, Maude A. Liegeois, Bruce Wang, Kwun Wah Wen, Grace E. Kim, Eric Andrew Collisson, Stephan Krüger, Stefan Hubert Boeck, Steffen Ormanns, , Rushika M. Perera

This study identifies PCSK9 as a key determinant of metastatic organ preference in pancreatic cancer by regulating cholesterol acquisition and utilization in liver versus lung environments.

bioRxiv · Apr 22, 2025 · PreprintCancer Biology

nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer

Audrey M. Hendley, Sudipta Ashe, Atsushi Urano, Martin Ng, Tuan Anh Phu, Xianlu L. Peng, Changfei Luan, Anna‐Marie Finger, Gun Ho Jang, Natanya R. Kerper, David I. Berrios, David S. Jin, Jonghyun Lee, Irene Riahi, Oghenekevwe M. Gbenedio, , Matthias Hebrok

This study shows that eliminating nSMase2 in pancreatic cancer reduces tumor growth, promotes a less aggressive tumor subtype, and enhances immune responses by altering exosome production and macrophage polarization.

bioRxiv · Sep 23, 2024 · PreprintCancer Biology