Author

Gregor Kirfel

University of Bonn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Hubert SchorleiD· 2 shared Lena ArévaloiD· 2 shared Simon SchneideriD· 2 shared Alexander KruseiD· 1 shared Andjela KovaceviciD· 1 shared Andreas Christian FröbiusiD· 1 shared Ann‐Kristin DickeiD· 1 shared Christoph BrenkeriD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersDevelopmental Biology

Hubert SchorleORCID

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2 papers

Recent·Most cited

Cylicins are a structural component of the sperm calyx being indispensable for male fertility in mice and human

Simon Schneider, Andjela Kovacevic, Michelle Mayer, Ann‐Kristin Dicke, Lena Arévalo, Sophie A. Koser, Jan N. Hansen, Samuel Young, Christoph Brenker, Sabine Kliesch, Dagmar Wachten, Gregor Kirfel, Timo Strünker, Frank Tüttelmann, Hubert Schorle

This study investigates the role of Cylicins in spermiogenesis and male fertility using gene-editing in mice and exome sequencing in humans, finding that Cylicin deficiency causes infertility and structural sperm abnormalities.

eLife · Nov 28, 2023Peer-reviewedDevelopmental Biology

Loss of Prm1 leads to defective chromatin protamination, impaired PRM2 processing, reduced sperm motility and subfertility in male mice

Gina Esther Merges, Julia C. Meier, Simon Schneider, Alexander Kruse, Andreas Christian Fröbius, Gregor Kirfel, Klaus Steger, Lena Arévalo, Hubert Schorle

This study shows that Prm1 deficiency in mice causes DNA damage, impaired PRM2 processing, and subfertility due to disrupted chromatin protamination.

Development · May 24, 2022Peer-reviewedDevelopmental Biology