Author

Andreas Christian Fröbius

Justus-Liebig-Universität GießenORCID 0000-0002-0343-6067Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander KruseiD· 2 shared Gina Esther MergesiD· 2 shared Hubert SchorleiD· 2 shared Klaus StegeriD· 2 shared Simon SchneideriD· 2 shared Axel ImhofiD· 1 shared Gregor Kirfel· 1 shared Ignasi FornéiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Alexander KruseORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular Human ReproductionPeer-reviewedJan 1, 2025

An aberrant protamine ratio is associated with decreased H4ac levels in murine and human sperm

Alexander Kruse, Simon Schneider, Gina Esther Merges…·Klaus Steger

The paper investigates the relationship between protamine ratios and histone acetylation levels in sperm from mice and humans, finding reduced H4ac levels associated with altered protamine ratios.

2 citations

mousehuman

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Developmental BiologyDevelopmentPeer-reviewedMay 24, 2022

Loss of Prm1 leads to defective chromatin protamination, impaired PRM2 processing, reduced sperm motility and subfertility in male mice

Gina Esther Merges, Julia C. Meier, Simon Schneider…·Hubert Schorle

This study shows that Prm1 deficiency in mice causes DNA damage, impaired PRM2 processing, and subfertility due to disrupted chromatin protamination.

54 citationstop 1%

mouseproteomics

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