Klaus Steger

An aberrant protamine ratio is associated with decreased H4ac levels in murine and human sperm

The paper investigates the relationship between protamine ratios and histone acetylation levels in sperm from mice and humans, finding reduced H4ac levels associated with altered protamine ratios.

Protamine 2 Deficiency Results In Septin 12 Abnormalities

This study shows that Protamine 2 deficiency leads to Septin 12 abnormalities in sperm, affecting motility and morphology.

Loss of Prm1 leads to defective chromatin protamination, impaired PRM2 processing, reduced sperm motility and subfertility in male mice

This study shows that Prm1 deficiency in mice causes DNA damage, impaired PRM2 processing, and subfertility due to disrupted chromatin protamination.

Prm2 deficiency triggers a Reactive Oxygen Species (ROS)-mediated destruction cascade during epididymal sperm maturation in mice

This study investigates Prm2 deficiency in mice, showing it leads to oxidative stress and DNA damage during sperm maturation, affecting fertility.