H. Cai

This study identifies a high-affinity nanobody that, when fused to other nanobodies, enhances their potency against SARS-CoV-2 by improving RBD binding without disrupting RBM conformation.

This study identifies miR775 as a regulator of leaf size in Arabidopsis by silencing GALT9, a galactosyltransferase that affects cell wall pectin levels and elasticity.

This study evaluates three fecal immunoassay technologies for detecting canine Echinococcus infection in China, finding that sensitivity is lower than expected and further development is needed.

This paper develops an acoustofluidic method to controllably fuse human brain organoids, enhancing standardization and reproducibility of fused models.

This study investigates how the marine ciliate Mesodinium rubrum controls sequestered cryptophyte organelles, finding limited transcriptional control and significant gene expression from the prey.

This study uses whole genome sequencing to identify potential new antimicrobial resistance mechanisms in Mycoplasma bovis by comparing high and low MIC isolates.

This study restores vision in blind mice by reprogramming Muller glia to retinal neurons, demonstrating a potential treatment for end-stage retinal degeneration.

This paper introduces an acoustofluidic device to create 3D neurospheroids for modeling Alzheimer's disease neuroinflammation and amyloid-β toxicity.

The paper examines non-linear trait responses to a continuous soil moisture gradient in Brachypodium species using function-valued traits and statistical methods.

This paper introduces G-baToN, a reporter system that labels cell-cell interactions through fluorescent protein transfer, enabling study of cancer-stromal cell interactions and other biological processes.

The paper uses a quantitative platform and statistical methods to map pharmacogenomic responses in lung cancer, revealing complex genotype-specific therapeutic interactions.

This paper develops a microfluidic platform to assemble human brain organoids and models prenatal cannabis exposure effects on early brain development.

The paper shows that boron deficiency reduces brassinolide accumulation by downregulating BR6ox1 and BR6ox2, thereby inhibiting root growth through BR signaling.

This study shows that 2'3'-cGAMP activates dSTING and NF-κB to trigger a broad antiviral response in Drosophila, independent of autophagy and RNAi pathways.

This study identifies axon-like protrusions in SCLC cells as drivers of migration and metastasis, linking neuronal programs to cancer progression.

This study shows that neogambogic acid inhibits osteosarcoma by targeting the USP9x/SOX2 axis through ubiquitin proteasome-mediated degradation of SOX2.

This paper establishes a multilocus sequence analysis (MLSA) method using six protein-coding genes to classify Shewanella strains, revealing evolutionary relationships and population biology.