Author

W.-Y. Lin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 2 Bioengineering· 1 Genetics· 1 Microbiology· 1 Plant Biology· 1

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

C. Li· 3 shared H. Cai· 3 shared M. M. Winslow· 3 shared D. Li· 2 shared D. Petrov· 2 shared D. R. Littman· 2 shared H. M. Silva· 2 shared L. Andrejka· 2 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersCancer Biology

C. Li

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Author profile →

9 papers

Recent·Most cited

Comparison of Multiple Carbapenemase Tests Based on an Unbiased Colony Selection Method

H.-Y. Wang, Y.-J. Tseng, W.-Y. Lin, Y.-C. Wang, T.-W. Lin, J.-F. Hsu, M. Y.-C. Wu, C.-H. Wu, S. Kalpana, J.-J. Lu

This study compares carbapenemase tests using an unbiased colony selection method, finding improved detection and highlighting performance discrepancies among tests.

Biomedicines · Sep 20, 2024Peer-reviewedMicrobiology

StomaVision: stomatal trait analysis through deep learning

T.-L. Wu, P.-Y. Chen, X. Du, H. Wu, J.-Y. Ou, P.-X. Zheng, Y.-L. Wu, R.-S. Wang, T.-C. Hsu, C.-Y. Lin, W.-Y. Lin, P.-L. Chang, C.-M. K. Ho, Y.-C. Lin

StomaVision automates stomatal trait analysis from micrographs, revealing physiological responses to heat stress across plant species.

bioRxiv · Apr 24, 2024 · PreprintPlant Biology

A Noninvasive Skin Biopsy of Free Nerve Endings via Realtime Third-Harmonic Microscopy

P. J. Wu, H.-C. Tseng, C.-C. Chao, Y.-H. Liao, C.-T. Yen, W.-Y. Lin, S.-T. Hsieh, W.-Z. Sun, C.-K. Sun

This paper introduces a non-invasive third-harmonic microscopy technique to image free nerve endings and quantitatively assess small fiber neuropathy.

bioRxiv · Dec 14, 2022 · PreprintBioengineering

Combinatorial tumor suppressor inactivation efficiently initiates lung adenocarcinoma with therapeutic vulnerabilities

M. Yousefi, G. Boross, C. Weiss, C. W. Murray, J. D. Hebert, H. Cai, E. L. Ashkin, S. Karmakar, L. Andrejka, L. Chen, M. Wang, M. K. Tsai, W.-Y. Lin, C. Li, P. Yakhchalian, , M. M. Winslow

This study identifies RAS/PI3K pathway activation as a common driver in oncogene-negative lung adenocarcinomas and shows these tumors are vulnerable to targeted therapy.

bioRxiv · Oct 20, 2021Cancer Biology

Genetic determinants of EGFR-Driven Lung Cancer Growth and Therapeutic Response In Vivo

G. Foggetti, C. Li, H. Cai, J. Hellyer, W.-Y. Lin, D. Ayeni, K. Hastings, J. Choi, A. Wurtz, L. Andrejka, D. Maghini, N. Rashleigh, S. Levy, R. Homer, S. Gettinger, , K. Politi

This study investigates how genetic alterations affect EGFR-driven lung cancer growth and therapy response using a mouse model and CRISPR-Cas9 editing.

Cancer Discovery · Mar 11, 2021Peer-reviewedCancer Biology

Niche-selective inhibition of pathogenic Th17 cells by targeting metabolic redundancy

L. Wu, K. E. R. Hollinshead, Y. Hao, C. Au, L. Kroehling, C. Ng, W.-y. Lin, D. Li, H. M. Silva, J. Shin, J. J. Lafaille, R. Possemato, M. E. Pacold, T. Y. Papagiannakopoulos, A. C. Kimmelman, , D. R. Littman

This study shows that targeting Gpi1 selectively inhibits pathogenic Th17 cells in autoimmune diseases while sparing homeostatic Th17 cells.

bioRxiv · Jun 10, 2020Immunology

Quantitative in vivo analyses reveal a complex pharmacogenomic landscape in lung adenocarcinoma

C. Li, W.-Y. Lin, H. Rizvi, H. Cai, C. D. McFarland, Z. N. Rogers, M. Yousefi, I. P. Winters, C. M. Rudin, D. Petrov, M. M. Winslow

The paper uses a quantitative platform and statistical methods to map pharmacogenomic responses in lung cancer, revealing complex genotype-specific therapeutic interactions.

bioRxiv · Jan 28, 2020Cancer Biology

Serum Amyloid A Proteins Induce Pathogenic TH17 Cells and Promote Inflammatory Disease

J.-Y. Lee, J. A. Hall, L. Kroehling, L. Wu, T. Najar, H. H. Nguyen, W.-Y. Lin, S. T. Yeung, H. M. Silva, D. Li, A. Hine, P. Loke, D. Hudesman, J. C. Martin, E. Kenigsberg, , D. R. Littman

This study shows serum amyloid A proteins drive pathogenic TH17 cell differentiation and promote inflammatory disease through STAT3-activating cytokines.

bioRxiv · Jun 25, 2019Immunology

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

E. Evangelou, H. R. Warren, D. Mosen-Ansorena, B. Mifsud, R. Pazoki, H. Gao, G. Ntritsos, N. Dimou, C. P. Cabrera, I. Karaman, F. L. Ng, M. Evangelou, K. Witkowska, E. Tzanis, J. N. Hellwege, , Verwe

This study identifies 535 novel genetic loci associated with blood pressure traits in over one million individuals of European ancestry.

bioRxiv · Oct 11, 2017 · PreprintGenetics