H. Cao

This study identifies the lncRNA PLANE as a regulator of alternative splicing that promotes cancer progression by repressing NCOR2-202 splicing, leading to poor patient outcomes.

Introgression of the 1Ay21* HMW-GS increases wheat grain protein content and improves bread-making quality by reshaping the grain proteome network.

The paper identifies a potent neutralizing nanobody against SARS-CoV-2 with high activity and stability for inhaled delivery.

This study demonstrates that customized speckle patterns can achieve three times higher spatial resolution than the diffraction limit in parallelized nonlinear pattern-illumination microscopy.

The paper identifies Fbxo45 as a N-cadherin-binding protein that regulates neuron migration by interacting with SPRY motifs in the extracellular domain of N-cadherin.

This study quantifies the Zn uptake and distribution requirements needed to achieve high grain Zn concentration in high-yield wheat on low-Zn calcareous soils.

This study identifies an insertion sequence in SARS-CoV-2 spike protein that enhances cleavage efficiency and expands tissue tropism beyond the lungs.

This study identifies human lncRNA metabolic regulators (hLMRs) using integrative transcriptome analyses and humanized mouse models, validating one hLMR's role in cholesterol metabolism.

This study identifies a novel G protein-biased and subtype-selective agonist for the 5-HT2C receptor from herbal extracts, showing efficacy in weight loss similar to lorcaserin.

This study compares the shapes and sizes of prostate lesions in dogs treated with laser, radiofrequency, and microwave ablation, finding significant differences in lesion morphology and volume.

The paper identifies a multidrug-resistant P. aeruginosa strain with hyperactive quorum sensing that enhances virulence and resistance.

This study improves heterologous protein production in Bacillus subtilis by rewiring nitrogen and carbon metabolic regulatory networks through mutations in CodY and CcpA, increasing yields up to 290%.

This study shows that gut metabolite UA reduces T cell proliferation by increasing miR-10a-5p and decreasing Orai1/STIM1/STIM2 expression and SOCE in murine CD4+ T cells.