Author

H. Colman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:Drosophila· 1 Approach:experimental assay· 1

Frequent Co-Authors

S. M. Arnold· 2 shared A. C. Boese· 1 shared A. Chakravarti· 1 shared A. I. Marcus· 1 shared A. R. Post· 1 shared A. S. Silva· 1 shared A. Shcheglovitov· 1 shared B. B. Morris· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

S. M. Arnold

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Author profile →

3 papers

Recent·Most cited

Transcriptional changes consistent with altered neuronal differentiation, angiogenesis, and tumor plasticity induced in human subpallial telencephalic organoid-glioblastoma chimeras.

S. Chiola, J. Yang, H. M. A. Ullah, K. Napan, Q. Huang, N. Gamboa, O. Youssef, H. Colman, S. Cheshier, A. Shcheglovitov

This study investigates reciprocal interactions between human subpallial telencephalic organoids and GBM spheroids, identifying transcriptional changes linked to neuronal differentiation, angiogenesis, and tumor plasticity.

bioRxiv · May 11, 2023 · PreprintCancer Biology

Loss of the endocytic tumor suppressor HD-PTP phenocopies LKB1 and promotes RAS-driven oncogenesis.

C.-S. Seong, C. Huang, A. C. Boese, Y. Hou, J. Koo, J. K. Mouw, M. Rupji, G. Joseph, H. R. Johnston, H. Claussen, J. M. Switchenko, M. Behera, M. Churchman, J. M. Kolesar, S. M. Arnold, , M. Gilbert-Ross

The paper shows that loss of HD-PTP, a tumor suppressor, promotes RAS-driven oncogenesis and is associated with adenosquamous lung cancer, suggesting it as a therapeutic target.

bioRxiv · Jan 26, 2023 · PreprintCancer Biology

Replicative Instability Drives Cancer Progression

B. B. Morris, J. P. Smith, Q. Zhang, Z. Jiang, O. A. Hampton, M. L. Churchman, S. M. Arnold, D. H. Owen, J. E. Gray, P. M. Dillon, H. H. Soliman, D. G. Stover, H. Colman, A. Chakravarti, K. H. Shain, , M. W. Mayo

This study identifies a pan-cancer class of tumors driven by replicative instability, showing it accelerates cancer progression through genomic changes and transcriptional rewiring.

bioRxiv · May 6, 2022Cancer Biology