Author

H. Farhan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

V. Reiterer· 3 shared M. Zahoor· 2 shared S. Geley· 2 shared S. Phuyal· 2 shared A. Iyer· 1 shared A. Kohn-Luque· 1 shared A.-L. Le Roux· 1 shared C. Behrends· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCell Biology

V. Reiterer

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Author profile →

4 papers

Recent·Most cited

Identification of a link between splicing and endoplasmic reticulum proteostasis

H. Farhan, M. Zahoor, Y. Dong, M. Preussner, S. Shameen Alam, R. Hajdu, V. Reiterer, S. Geley, V. Cormier-Daire, F. Heyd, L. A. Jerome-Majewska

This study identifies SNRPB as a regulator of ER export and links it to osteogenesis and CCMS through its effects on splicing and the UPR.

bioRxiv · Sep 28, 2023 · PreprintCell Biology

A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression

S. Ghannoum, D. Fantini, M. Zahoor, V. R. Farhan, S. Phuyal, W. L. Netto, O. Sorensen, A. Iyer, D. Sengupta, L. Prasmickaite, G. M. Malandsmo, A. Kohn-Luque, H. Farhan

The paper develops a computational model to study cell migration traits in tumor progression and finds that Giantin depletion increases intravasation, validated by lower Giantin levels in circulating tumor cells.

bioRxiv · Apr 25, 2022Cancer Biology

Mechanical strain stimulates COPII-dependent trafficking via Rac1

H. Farhan, S. Phuyal, P. Roca-Cusachs, S. Geley, V. Reiterer, D. Teis, D. Fankhauser, J. Kahlhofer, A.-L. Le Roux, M. Baker, M. Kazanietz, L. A. Eriksson, S. J. Mahdizadeh, E. Djaerff

The paper shows mechanical strain regulates COPII-dependent ER-export through Rac1-mediated mechanotransduction.

bioRxiv · Jan 23, 2022 · PreprintCell Biology

LTK is an ER-resident receptor tyrosine kinase that regulates secretion

F. G. Centonze, V. Reiterer, K. Nalbach, K. Saito, K. Pawlowski, C. Behrends, H. Farhan

This study identifies LTK as an ER-resident receptor tyrosine kinase that regulates ER exit sites and ER-to-Golgi transport through interaction and phosphorylation of Sec12.

bioRxiv · Mar 13, 2019Cell Biology