Author

S. Phuyal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:chicken / avian· 1 Research Focus:clustering· 1

Frequent Co-Authors

H. Farhan· 2 shared A. Brech· 1 shared A. H. Lystad· 1 shared A. Iyer· 1 shared A. Kohn-Luque· 1 shared A.-L. Le Roux· 1 shared B. J. Walker· 1 shared C. Raiborg· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCancer Biology

H. Farhan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lysosome repair by ER-mediated cholesterol transfer

M. Radulovic, E. M. Wenzel, S. Gilani, L. K. K. Holland, A. H. Lystad, S. Phuyal, V. M. Olkkonen, A. Brech, M. Jäättelä, K. Maeda, C. Raiborg, H. Stenmark

The paper identifies an ER-mediated cholesterol transfer mechanism for lysosome repair independent of ESCRTs, involving PI4K2A and OSBP.

bioRxiv · Sep 26, 2022 · PreprintCell Biology

A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression

S. Ghannoum, D. Fantini, M. Zahoor, V. R. Farhan, S. Phuyal, W. L. Netto, O. Sorensen, A. Iyer, D. Sengupta, L. Prasmickaite, G. M. Malandsmo, A. Kohn-Luque, H. Farhan

The paper develops a computational model to study cell migration traits in tumor progression and finds that Giantin depletion increases intravasation, validated by lower Giantin levels in circulating tumor cells.

bioRxiv · Apr 25, 2022Cancer Biology

Mechanical strain stimulates COPII-dependent trafficking via Rac1

H. Farhan, S. Phuyal, P. Roca-Cusachs, S. Geley, V. Reiterer, D. Teis, D. Fankhauser, J. Kahlhofer, A.-L. Le Roux, M. Baker, M. Kazanietz, L. A. Eriksson, S. J. Mahdizadeh, E. Djaerff

The paper shows mechanical strain regulates COPII-dependent ER-export through Rac1-mediated mechanotransduction.

bioRxiv · Jan 23, 2022 · PreprintCell Biology

Computer-assisted beat-pattern analysis and the flagellar waveforms of bovine spermatozoa

B. J. Walker, S. Phuyal, K. Ishimoto, C.-K. Tung, E. A. Gaffney

This paper introduces a high-fidelity computer-assisted beat-pattern analysis method for bovine sperm flagellar waveforms, demonstrating statistical comparisons and synthetic data generation.

bioRxiv · Mar 6, 2020Microbiology