Author

H. Suemizu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Grompe· 2 shared A. Ding· 1 shared A. F. Stenzel· 1 shared A. W. Ashbrook· 1 shared B. A. Ersoy· 1 shared B. Razooky· 1 shared B. Zeck· 1 shared C. Bear· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

M. Grompe

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Generation of functional ciliates cholangiocytes from human pluripotent stem cells

M. Ogawa, J.-X. Jiang, S. Xia, D. Yang, A. Ding, O. Laselva, S. Chin, M. Hernandez, C. Cui, Y. Higuchi, H. Suemizu, C. Dorrell, M. Grompe, C. Bear, G. Keller, S. Ogawa

This study generates functional cholangiocytes from human pluripotent stem cells that exhibit mature characteristics and can be used for drug testing and disease modeling.

bioRxiv · Mar 23, 2021Cell Biology

Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic steatohepatitis development in chimeric mice

M. Kabbani, E. Michailidis, S. Steensels, C. G. Fulmer, J. M. Luna, J. Le Pen, M. Tardelli, B. Razooky, I. Ricardo-Lax, C. Zou, B. Zeck, A. F. Stenzel, C. Quirk, L. Foquet, A. W. Ashbrook, , Y. P. de Jong

This study shows that the PNPLA3 148M variant in human hepatocytes worsens non-alcoholic steatohepatitis in chimeric mice on a hypercaloric diet.

bioRxiv · Nov 19, 2020 · PreprintPathology

Multilevel integrative transcriptome analyses in humans and humanized mice define in vivo human lncRNA metabolic regulators

X. Ruan, P. Li, Y. Ma, C.-f. Jiang, Y. Chen, Y. Shi, N. Gupta, F. Seifuddin, M. Pirooznia, H. Suemizu, Y. Ohnishi, N. Yoneda, M. Nishiwaki, H. Cao

This study identifies human lncRNA metabolic regulators (hLMRs) using integrative transcriptome analyses and humanized mouse models, validating one hLMR's role in cholesterol metabolism.

bioRxiv · Jan 1, 2020Physiology