Author

M. Grompe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

H. Suemizu· 2 shared A. Ding· 1 shared A. F. Stenzel· 1 shared A. G. Paulovich· 1 shared A. L. H. Webster· 1 shared A. Smogorzewska· 1 shared A. W. Ashbrook· 1 shared B. A. Ersoy· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

H. Suemizu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cell networks in the mouse liver during partial hepatectomy

B. Li, D. Rodrigo-Torres, C. Pelz, B. T. Innes, P. Canaday, S. Chai, P. Zandstra, G. Bader, M. Grompe

The paper identifies and validates novel signaling interactions in liver regeneration using a computational platform analyzing cell-cell interactions in mouse livers.

bioRxiv · Jul 16, 2023 · PreprintCell Biology

Fanconi anemia-isogenic head and neck cancer cell line pairs - a basic and translational science resource

H. T. Nguyen, W. Tang, A. L. H. Webster, J. R. Whiteaker, C. M. Chandler, R. Errazquin, L. B. Sullivan, E. Jonlin, E. E. Hoskins, E. Y. Chen, M. Fritzke, A. G. Paulovich, S. I. Wells, K. Roohollahi, J. Dorsman, , R. J. Monnat

The paper develops isogenic head and neck cancer cell line pairs to study Fanconi anemia-associated cancers and their treatment.

bioRxiv · Sep 11, 2022Cancer Biology

Rapid in vivo multiplexed editing (RIME) of the adult mouse liver

T. Katsuda, H. Cure, K. P. Simeonov, Z. Arany, M. Grompe, B. Stanger

This paper introduces RIME, a method for rapid in vivo gene editing in adult mouse liver, demonstrating efficient knockout of multiple genes.

bioRxiv · Mar 4, 2022Physiology

Generation of functional ciliates cholangiocytes from human pluripotent stem cells

M. Ogawa, J.-X. Jiang, S. Xia, D. Yang, A. Ding, O. Laselva, S. Chin, M. Hernandez, C. Cui, Y. Higuchi, H. Suemizu, C. Dorrell, M. Grompe, C. Bear, G. Keller, S. Ogawa

This study generates functional cholangiocytes from human pluripotent stem cells that exhibit mature characteristics and can be used for drug testing and disease modeling.

bioRxiv · Mar 23, 2021Cell Biology

Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic steatohepatitis development in chimeric mice

M. Kabbani, E. Michailidis, S. Steensels, C. G. Fulmer, J. M. Luna, J. Le Pen, M. Tardelli, B. Razooky, I. Ricardo-Lax, C. Zou, B. Zeck, A. F. Stenzel, C. Quirk, L. Foquet, A. W. Ashbrook, , Y. P. de Jong

This study shows that the PNPLA3 148M variant in human hepatocytes worsens non-alcoholic steatohepatitis in chimeric mice on a hypercaloric diet.

bioRxiv · Nov 19, 2020 · PreprintPathology