Author

M. Pirooznia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Physiology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

F. Seifuddin· 2 shared K. Singh· 2 shared Y. Li· 2 shared A. J. Nelson· 1 shared A. M. Aponte· 1 shared A. S. Baez· 1 shared B. S. Collins· 1 shared B. S. Turner· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

F. Seifuddin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Social Determinants modulate NK cell activity via obesity, LDL, and DUSP1 signaling

Y. Baumer, K. Singh, A. S. Baez, C. A. Gutierrez-Huerta, L. Cheng, M. Igboko, B. S. Turner, J. A. Yeboah, R. N. Reger, L. R. Ortiz-Whittingham, C. K. Bleck, V. M. Mitchell, B. S. Collins, M. Pirooznia, P. K. Dagur, , T. M. Powell-Wiley

The paper links adverse social determinants of health to NK cell dysfunction through obesity, LDL, and DUSP1 signaling in African-American women.

bioRxiv · Sep 12, 2023 · PreprintImmunology

Metabolic design in a model of extreme mammalian metabolism, the North American least shrew (Cryptotis parva)

D. J. Chung, G. P. Madison, A. M. Aponte, K. Singh, Y. Li, M. Pirooznia, C. K. E. Bleck, N. A. Darmani, R. S. Balaban

The paper examines mitochondrial structure and function in the least shrew, revealing organ-specific adaptations in mitochondrial networks and protein composition related to metabolic demand.

bioRxiv · May 28, 2021Zoology

Acetylation-mediated phase control of the nucleolus regulates cellular acetyl-CoA responses

R. Houston, S. Sekine, M. J. Calderon, F. Seifuddin, G. Wang, H. Kawagishi, D. A. Malide, Y. Li, M. Gucek, M. Pirooznia, A. J. Nelson, M. P. Stokes, J. Stewart-Ornstein, S. G. Wendell, S. C. Watkins, , Y. Sekine

The paper shows that acetyl-CoA depletion disrupts nucleolar integrity, activates p53 via ribosomal proteins, and is mediated by class IIa HDACs regulating nucleolar phase state.

bioRxiv · Jan 24, 2020Cell Biology

Multilevel integrative transcriptome analyses in humans and humanized mice define in vivo human lncRNA metabolic regulators

X. Ruan, P. Li, Y. Ma, C.-f. Jiang, Y. Chen, Y. Shi, N. Gupta, F. Seifuddin, M. Pirooznia, H. Suemizu, Y. Ohnishi, N. Yoneda, M. Nishiwaki, H. Cao

This study identifies human lncRNA metabolic regulators (hLMRs) using integrative transcriptome analyses and humanized mouse models, validating one hLMR's role in cholesterol metabolism.

bioRxiv · Jan 1, 2020Physiology