H. Yoo

H2O2 sulfenylates CHE linking local infection to establishment of systemic acquired resistance

The paper identifies H2O2-mediated sulfenylation of CHE as a mechanism for systemic acquired resistance in plants.

YAP/TAZ inactivation with simvastatin attenuates glucocorticoid-induced human trabecular meshwork cell dysfunction

This study shows that simvastatin reduces YAP/TAZ activity and ECM dysfunction in glucocorticoid-treated human trabecular meshwork cells.

Effects of netarsudil-family Rho kinase inhibitors on human trabecular meshwork cell contractility and actin remodeling using a bioengineered ECM hydrogel

Engineering a 3D hydrogel system to study optic nerve head astrocyte morphology and behavior in response to glaucomatous insult

This study develops a 3D hydrogel system to mimic the in vivo mouse optic nerve head astrocyte microenvironment and assesses their reactivity to TGFβ2 treatment.

Intelligent Resolution: Integrating Cryo-EM with AI-driven Multi-resolution Simulations to Observe the SARS-CoV-2 Replication-Transcription Machinery in Action

This study develops an AI-driven multi-resolution simulation workflow to study SARS-CoV-2 RTC dynamics, combining cryo-EM with mesoscale simulations and AI methods.

Chaperones directly and efficiently disperse stress-triggered biomolecular condensates

This study shows that the yeast disaggregation system efficiently disperses heat-induced Pab1 condensates, revealing distinct molecular requirements compared to model substrates.

The FACT complex is required for DNA demethylation at heterochromatin during reproduction in Arabidopsis

This study shows that the FACT complex facilitates DME-mediated DNA demethylation at heterochromatin during Arabidopsis reproduction by enabling access to GC-rich, nucleosome-dense regions.