Author

B. Hong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 3 Biophysics· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:human· 4 Organism:plant (other)· 4 Assay:proteomics· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

C. Paetz· 3 shared H. Fan· 3 shared S. E. O'Connor· 3 shared Y. Nakamura· 3 shared H. Zhuang· 2 shared K. Xiang· 2 shared L. Caputi· 2 shared L. Wang· 2 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

C. Paetz

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Exogenous Methylglyoxal Improves Maize Yield by Alleviating Plant Diabetes and leaf senescence under Drought

Y.-H. Lin, Y.-N. Zhou, Y.-k. Jin, Z.-D. Xiao, Y.-J. Zhang, C. Huang, B. Hong, S. Shen, S.-L. Zhou

This study shows exogenous methylglyoxal alleviates drought-induced leaf senescence and yield loss in maize by improving sugar metabolism and activating defense pathways.

bioRxiv · Jul 18, 2023 · PreprintPhysiology

Recycling upstream redox enzymes expands the regioselectivity of cycloaddition in pseudo-aspidosperma alkaloid biosynthesis

M. O. Kamileen, M. DeMars, B. Hong, Y. Nakamura, C. Paetz, B. R. Lichman, P. D. Sonawane, L. Caputi, S. E. O'Connor

The paper shows that redox enzymes can alter the regioselectivity of cycloaddition reactions in alkaloid biosynthesis, enabling the formation of pseudo-aspidosperma alkaloids.

bioRxiv · Sep 13, 2022Biochemistry

Expansion of the Catalytic Repertoire of Alcohol Dehydrogenases in Plant Metabolism

C. Langley, E. E. Tatsis, B. Hong, Y. Nakamura, C. Paetz, C. E. M. Stevenson, J. Basquin, D. M. Lawson, L. Caputi, S. E. O'Connor

The paper reports the crystal structure of an ADH enzyme that catalyzes a non-canonical 1,4 reduction, providing insights into how plant ADHs diversify their catalytic functions.

bioRxiv · Jul 24, 2022Biochemistry

Pathogen-Host Adhesion between SARS-CoV-2 S Proteins from Different Variants and Human ACE2 Probed at Single-Molecule and Single-Cell Levels

X. Zhang, J. Chen, B. Hong, H. Xu, P. Pei, L. Chen, Y. Tong, S.-Z. Luo, H. Fan, C. He

This study investigates the adhesion of SARS-CoV-2 S proteins from different variants to human ACE2 using single-molecule and single-cell force spectroscopy, finding Delta variant has the highest binding affinity.

bioRxiv · Jun 5, 2022 · PreprintBiophysics

The Human walking kinematic model combined with upper and lower limb movement

X. Chen, B. Hong, Z. Lin, J. Hou, S. Lv, Z. Gao

This study builds a human walking kinematic model combining lower limb rolling-foot and upper limb multi-rod swinging models, showing good agreement between experimental and theoretical joint velocity calculations.

bioRxiv · Feb 6, 2021 · PreprintBiophysics

SARS-CoV-2 and Malayan pangolin coronavirus infect human endoderm, ectoderm and induced lung progenitor cells

K. Xiang, B. Hong, X. Lai, Y. Chen, T. Luo, X. An, L. Song, H. Zhuang, H. Fan, T. Li, Y.-G. Tong

This study shows SARS-CoV-2 and GX_P2V can infect human endoderm, ectoderm, and lung progenitor cells derived from hESCs, with some infections blocked by whey protein and Remdesivir.

bioRxiv · Sep 25, 2020 · PreprintMicrobiology

Two bi-functional cytochrome P450 CYP72 enzymes from olive (Olea europaea) catalyze the oxidative C-C bond cleavage in the biosynthesis of secoxy-iridoids - flavor and quality determinants in olive oil

C. E. Rodriguez-Lopez, B. Hong, C. Paetz, Y. Nakamura, K. Koudounas, V. Passeri, L. Baldoni, F. Alagna, O. Calderini, S. E. O'Connor

This study identifies two bi-functional CYP72 enzymes in olive that catalyze oxidative C-C bond cleavage in secoxy-iridoid biosynthesis, revealing a secologanin-independent pathway and linking domestication to gene expression.

bioRxiv · Aug 28, 2020Biochemistry

The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro

H. Fan, Y. Luo, B. Hong, L. Wang, X. Jin, Y. Chen, Y. Hu, T. Li, H. Zhuang, Y.-H. Zhou, Y.-G. Tong, K. Xiang

This study shows that whey protein from human and other animal milk inhibits SARS-CoV-2 and GX_P2V in vitro by blocking viral attachment, entry, and replication.

bioRxiv · Aug 17, 2020Microbiology

Snipe: Highly sensitive pathogen detection from metagenomic sequencing data

L. Huang, B. Hong, W. Yang, L. Wang, R. Yu

The paper introduces a method to improve pathogen detection in metagenomic data by correcting abundance estimates using species-specific genomic regions, enhancing sensitivity and specificity for low-abundance pathogens.

bioRxiv · May 6, 2020Microbiology