Author

T. T.-L. Ng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

G. K.-H. SIU· 3 shared H.-Y. Lao· 3 shared A. W.-T. Lee· 2 shared H. Chen· 2 shared H. Liu· 2 shared J. F.-W. Chan· 2 shared J. S.-L. LEUNG· 2 shared K. K.-W. To· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersMicrobiology

G. K.-H. SIU

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4 papers

Recent·Most cited

Comprehensive Identification of Pathogenic Microbes and Antimicrobial Resistance Genes in Food Products Using Nanopore Sequencing-Based Metagenomics

A. W.-T. Lee, I. C.-F. NG, E. Y.-K. WONG, I. T.-F. WONG, R. P.-P. SZE, K.-Y. CHAN, T.-Y. SO, Z. ZHANG, S. K.-Y. FUNG, S. C.-Y. WONG, W.-Y. TAM, H.-Y. Lao, L.-K. LEE, J. S.-L. LEUNG, C. T.-M. CHAN, , G. K.-H. SIU

This study uses nanopore sequencing to identify pathogens and antimicrobial resistance genes in food products, finding high prevalence of certain bacteria and resistance genes in specific food types.

Food Microbiology · Aug 1, 2024Peer-reviewedMicrobiology

Construction of lux-based promoter-reporter platforms in Mycobacterium bovis BCG for screening of drug repurposing small-molecule compounds as new anti-tuberculosis drugs

L. Zhu, A. W.-t. Lee, K. K.-L. WU, P. GAO, K. K.-G. Tam, R. Rajwani, G. C. CHABURTE, T. T.-L. NG, C. T. M. Chan, H.-Y. Lao, W.-C. Yam, R. Y.-T. Kao, G. K. H. Siu

This study constructs a lux-based promoter-reporter system to screen small-molecule compounds for anti-TB activity, identifying one antibiotic and two anti-virulence agents.

bioRxiv · Nov 5, 2021 · PreprintMicrobiology

Low dose inocula of SARS-CoV-2 B.1.1.7 variant initiate more robust infections in the upper respiratory tract of hamsters than earlier D614G variants

B. W.-Y. Mok, H. Liu, S.-Y. Lau, S. D. Deng, S. Liu, R. C.-Y. Tam, T. T.-L. Ng, J. S.-L. Leung, P. Wang, K. K.-W. To, J. F.-W. Chan, K.-H. Chan, K.-Y. Yuen, G. K.-H. Siu, H. Chen

This study shows that the B.1.1.7 SARS-CoV-2 variant replicates and sheds more efficiently in hamsters' nasal cavities than earlier D614G variants with lower doses and shorter exposure.

bioRxiv · Apr 19, 2021 · PreprintMicrobiology

SARS-CoV-2 spike D614G variant exhibits highly efficient replication and transmission in hamsters

B. W. Y. Mok, C. J. Cremin, S.-Y. Lau, S. Deng, P. Chen, A. J. Zhang, A. C.-Y. Lee, H. Liu, S. Liu, T. T.-L. Ng, H.-Y. Lao, E. L.-K. Lee, K. S.-S. Leung, P. Wang, K. K.-W. To, , H. Chen

This study compares SARS-CoV-2 strains in hamsters, finding that the D614G spike variant shows higher replication and transmission efficiency.

bioRxiv · Aug 28, 2020 · PreprintMicrobiology