A novel, evolutionarily conserved inhibitory circuit selectively regulates dentate gyrus mossy cell function.
Geoffrey A. Vargish, Haley Rice, Xiaoqing Q Yuan, Steven Hunt, Brendan E. Hines, Anya S. Plotnikova, Arya Mohanty, Elisabetta Furlanis, Yating Wang, Min Dai, Brenda Leyva Garcia, Alex C. Cummins, Mark A. G. Eldridge, Bruno B. Averbeck, Kareem A. Zaghloul, , Chris J. McBain
The paper identifies a novel inhibitory interneuron subtype in the dentate gyrus that selectively regulates mossy cell function and shows this pattern is evolutionarily conserved across species.
bioRxiv · Jul 9, 2025 · PreprintNeuroscience