Shuhan Huang

An enhancer-AAV toolbox to target and manipulate distinct interneuron subtypes

The paper identifies enhancer-AAV tools for specific neuronal subtypes and validates them across species.

Pyramidal neurons proportionately alter the identity and survival of specific cortical interneuron subtypes

The paper shows pyramidal neurons influence the survival and identity of specific interneuron subtypes through non-synaptic mechanisms.

Neurogliaform Cells Exhibit Laminar-specific Responses in the Visual Cortex and Modulate Behavioral State-dependent Cortical Activity

This study investigates neurogliaform cells in the visual cortex, showing their activity correlates with locomotion and their functional role is influenced by laminar position and connectivity.

Cortical somatostatin interneuron subtypes form cell-type specific circuits

The paper identifies cell-type specific circuits formed by subtypes of somatostatin interneurons in the cortex through genetic targeting and connectivity analysis.

Bottom-up inputs are required for the establishment of top-down connectivity onto cortical layer 1 neurogliaform cells

The paper shows that bottom-up thalamic inputs are essential for establishing top-down connectivity to layer 1 neurogliaform cells in the visual cortex during early development.

Viral manipulation of functionally distinct neurons from mice to humans

The paper identifies enhancers for targeting specific neuronal subtypes across species and demonstrates their utility in circuit manipulation.