Author

Hannah J. Lords

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:differential expression· 2 Assay:GWAS summary statistics· 2 Research Focus:GWAS / association mapping· 1 Research Focus:polygenic risk· 1 Assay:proteomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Harold T. BaeiD· 3 shared Paola Sebastiani BiD· 3 shared Stacy L. AnderseniD· 3 shared Thomas T. PerlsiD· 3 shared Anastasia LeshchykiD· 2 shared Marianne NygaardiD· 2 shared Mengze LiiD· 2 shared Zeyuan SongiD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersGenetics

Harold T. BaeORCID

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4 papers

Recent·Most cited

Genetic Modifiers of Cognitive Function: Novel Genetic Associations with Memory, Executive Function, and Attention in the Long Life Family Study

Hannah J. Lords, Mengze Li, Zeyuan Song, Anastasia Leshchyk, Harold T. Bae, Nicole Roth, Megan Short, Thomas T. Perls, Moon-Il Kang, Ting Fang Alvin Ang, Stephanie Cosentino, Sandra Barral, Marianne Nygaard, Konstantin G. Arbeev, Stacy L. Andersen, , Paola Sebastiani B

This study identifies genetic variants associated with cognitive domains like memory and attention using GWAS in the Long Life Family Study, finding domain-specific genetic architecture.

bioRxiv · Feb 3, 2026 · PreprintGenetics

Increased Genetic Protection Against Alzheimer's Disease in Centenarians

Harold T. Bae, Zeyuan Song, Amanat Ali, Takashi Sasaki, Niccoló Tesi, Hannah J. Lords, Anastasia Leshchyk, Yukiko Abe, Nobuyoshi Hirose, Yasumichi Arai, Nir Barzilai, Erica F Weiss, Marc Hulsman, Sven J. van der Lee, Natasja M. van Schoor, , Paola Sebastiani B

This study constructs a polygenic protective score for Alzheimer's disease and finds stronger genetic protection against AD in centenarians compared to non-longevity individuals.

GeroScience · Jul 4, 2025Peer-reviewedGenetics

Robust Serum Proteomic Signatures of APOE2

Paola Sebastiani B, Eric R. Reed, Kevin Brown Chandler, Prisma Lopez, Hannah J. Lords, Harold T. Bae, Catherine E. Costello, Matthew B. Au, Lingyi Lynn Deng, Mengze Li, Qingyan Xiang, Heeju Noh, Lance T. Pflieger, Cory C. Funk, Noa Rappaport, , Thomas T. Perls

The paper validates and expands a serum protein signature associated with APOE genotypes, identifying new protein associations and potential targets for Alzheimer's disease prevention.

bioRxiv · May 24, 2025 · PreprintGenetics

Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

Xiaolong Cao, Yeting Zhang, Lindsay M. Payer, Hannah J. Lords, Jared P. Steranka, Kathleen H. Burns, Jinchuan Xing

The paper identifies polymorphic mobile element insertions (pMEIs) as contributors to gene expression and alternative splicing variations across 48 human tissues using GTEx data.

Genome biology · Jul 27, 2020Peer-reviewedGenomics