Anastasia Leshchyk

Identification of novel plasma proteomic biomarkers of Dupuytren Disease

This study identifies novel plasma proteomic biomarkers for Dupuytren Disease, showing impaired Collagen I degradation and developing diagnostic risk scores with moderate accuracy.

Genetic Modifiers of Cognitive Function: Novel Genetic Associations with Memory, Executive Function, and Attention in the Long Life Family Study

This study identifies genetic variants associated with cognitive domains like memory and attention using GWAS in the Long Life Family Study, finding domain-specific genetic architecture.

Increased Genetic Protection Against Alzheimer's Disease in Centenarians

This study constructs a polygenic protective score for Alzheimer's disease and finds stronger genetic protection against AD in centenarians compared to non-longevity individuals.

Comprehensive generation, visualization, and reporting of quality control metrics for single-cell RNA sequencing data

The paper introduces a pipeline for generating, visualizing, and reporting quality control metrics for scRNA-seq data, improving standardization across platforms.

A Hybrid Deep Clustering Approach for Robust Cell Type Profiling Using Single-cell RNA-seq Data

This paper introduces a hybrid deep learning method for cell type clustering in scRNA-seq data, achieving performance comparable to supervised learning.