Author

Hasi Huhe

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Stacey J. Sukoff RizzoiD· 2 shared Adam K. HamdaniiD· 1 shared Adrian L. OblakiD· 1 shared Afonso C. SilvaiD· 1 shared Alan David Palkowitz· 1 shared Alexandra N. Faulkner· 1 shared Amantha ThathiahiD· 1 shared Andrew D. MesecariD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPharmacology & Toxicology

Stacey J. Sukoff RizzoORCID

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2 papers

Recent·Most cited

Optimization and Characterization of SHIP1 Ligands for Cellular Target Engagement and Activity in Alzheimer's Disease Models

Cynthia D. Jesudason, Claudia Rangel‐Barajas, Colin J Beach, Daniel E. Beck, Isaac Caballero-Floran, Brent Clayton, Lais Da Silva, Juliane C David, Suzanne Doolen, Alexandra N. Faulkner, Adam K. Hamdani, Hasi Huhe, Kevin Huynh, Ryan D. Imhoff, June Javens‐Wolfe, , Timothy I. Richardson

This study identifies SHIP1 ligands with brain exposure and in vivo activity in Alzheimer's models, showing target engagement and reduced neuroinflammation.

Journal of Medicinal Chemistry · Apr 30, 2026Peer-reviewedPharmacology & Toxicology

Marmosets as model systems for the study of Alzheimers disease and related dementias: substantiation of physiological Tau 3R and 4R isoform expression and phosphorylation

Hasi Huhe, Sarah M. Shapley, Duc Minh Duong, Fang Wu, Seung-Kwon Ha, Sangho Choi, Julia Kofler, Yongshan Mou, Thais Rafael Guimarães, Amantha Thathiah, Caroline M Watson, Lauren K Hayrynen Schaeffer, Gregory W. Carter, Nicholas T. Seyfried, Afonso C. Silva, Stacey J. Sukoff Rizzo

This study confirms the expression of 3R and 4R Tau isoforms and phosphorylation sites in marmoset brains, supporting their use as a model for Alzheimer's disease.

Alzheimer s & Dementia · Nov 19, 2024Peer-reviewedSystems Biology