Personalized Neoantigen Vaccines Synergize with Immune Checkpoint Therapy and CD8-Targeted Cytokines to Control B-Cell Lymphoma
Yuang Song, Ekaterina Aladyeva, Ruan F.V. Medrano, Derek J. Theisen, Cora D. Arthur, J. Michael White, Heather N. Kohlmiller, Anthony N. Vomund, Kartik Singhal, My Hoang, Samuel Ameh, Kathleen C. F. Sheehan, Ronald Levy, Todd A. Fehniger, Maxim N. Artyomov, , Robert D. Schreiber
This study shows that personalized neoantigen vaccines combined with immune checkpoint therapy and CD8-targeted cytokines effectively control B-cell lymphoma by enhancing T-cell responses and preventing dysfunction.
bioRxiv · Aug 6, 2026 · PreprintImmunology