In vivo high-throughput screening of novel adeno-associated viral capsids targeting adult neural stem cells in the subventricular zone
Sascha Dehler, Lukas P. M. Kremer, Santiago Cerrizuela, Thomas Stiehl, Jonas Weinmann, Heike Abendroth, Susanne Kleber, Alexander Laure, Jihad El Andari, Simon Anders, Anna K. Marciniak-Czochra, Dirk Grimm, Ana Martín-Villalba
The paper identifies AAV variants that efficiently target adult neural stem cells in the subventricular zone, enabling genetic modification for potential regenerative therapies.
bioRxiv · Mar 5, 2021 · PreprintNeuroscience