Author

I. A. Parish

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Nguyen· 1 shared C. C. Oakes· 1 shared C. D. Scharer· 1 shared C. Goodnow· 1 shared C. J. Kearney· 1 shared C. Szeto· 1 shared C. Weigel· 1 shared E. Masle-Farquhar· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperImmunology

A. Nguyen

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Author profile →

3 papers

Recent·Most cited

Type I interferon dynamics determines memory B cell epigenetic identity in chronic viral infection

L. Cooper, H. Xu, J. Polmear, C. Szeto, E. S. Pang, M. Gupta, J. J. Taylor, K. J. L. Jackson, A. Nguyen, N. La Gruta, L. G. Martelotto, I. A. Parish, M. O'Keeffe, C. D. Scharer, S. Gras, K. L. Good-Jacobson

The paper identifies type I interferon dynamics as a key factor shaping memory B cell development during chronic viral infection and shows that early IFNAR-1 blockade can reverse chromatin changes.

bioRxiv · Mar 2, 2023Immunology

Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint

E. Masle-Farquhar, T. J. Peters, L. A. Miosge, I. A. Parish, C. Weigel, C. C. Oakes, J. H. Reed, C. Goodnow

This study identifies EGR2 and EGR3 as critical transcription factors that suppress CD21low and B1 B cell accumulation by repressing plasma cell differentiation and follicular germinal center formation.

bioRxiv · Jul 1, 2021Immunology

Efficient CRISPR/Cas9 gene ablation in uncultured naive mouse T cells for in vivo studies

S. Nüssing, I. G. House, C. J. Kearney, S. J. Vervoort, P. A. Beavis, J. Oliaro, R. W. Johnstone, J. A. Trapani, I. A. Parish

This paper demonstrates efficient CRISPR/Cas9 gene ablation in uncultured naive mouse T cells for in vivo studies, showing gene deletion occurs independently of T cell activation.

bioRxiv · Aug 9, 2019Immunology