Author

I. Brodsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1

Frequent Co-Authors

A. A. Mironov· 1 shared A. Dukhovny· 1 shared A. Mironov· 1 shared A. Yeheskel· 1 shared B. Demarco· 1 shared C. Kaether· 1 shared C.-A. Assenmacher· 1 shared E. E. Zahavi· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. A. Mironov

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Human NAIP/NLRC4 and NLRP3 inflammasomes detect Salmonella type III secretion system activities to restrict intracellular bacterial replication

N. Naseer, M. Egan, V. Reyes Ruiz, I. Brodsky, S. Shin

This study shows that human NAIP/NLRC4 and NLRP3 inflammasomes detect Salmonella T3SS components, restricting bacterial replication in macrophages.

bioRxiv · Jun 17, 2021Microbiology

RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signalling

K. Chen, B. Demarco, R. Heilig, S. Ramos, J. Grayczyk, C.-A. Assenmacher, E. Radaelli, L. Joannas, J. Henao-Mejia, I. Brodsky, P. Broz

The paper shows that RIPK1 activates GSDME in neutrophils to promote anti-Yersinia defence through pyroptosis and IL-1β release.

bioRxiv · Jan 20, 2021Immunology

Uncoating of COPII from ER exit site membranes precedes cargo accumulation and membrane fission

O. Shomron, I. Nevo-Yassaf, T. Aviad, Y. Yaffe, E. E. Zahavi, A. Dukhovny, E. Perlson, I. Brodsky, A. Yeheskel, M. Pasmanik-Chor, A. Mironov, G. V. Beznoussenko, A. A. Mironov, E. H. Sklan, G. H. Patterson, , K. Hirschberg

The paper shows that COPII uncoating occurs before cargo accumulation and membrane fission during ER to Golgi transport.

bioRxiv · Aug 6, 2019Cell Biology