Author

E. Radaelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C.-A. Assenmacher· 3 shared A. Girona· 1 shared B. Demarco· 1 shared C. A. Hunter· 1 shared D. A. Christian· 1 shared D. P. Beiting· 1 shared D. Sorobetea· 1 shared E. Banerjee· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersCell Biology

C.-A. Assenmacher

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mitochondrial defects leading to arrested spermatogenesis and ferroptosis in a mouse model of Leigh Syndrome

E. Radaelli, C.-A. Assenmacher, E. Banerjee, F. Manero, S. Khiati, A. Girona, G. Lopez-Lluch, P. Navas, M. Spinazzi

This study shows that PARL deficiency in mice causes testicular atrophy and male infertility due to ferroptosis in spermatocytes, independent of neurodegeneration.

bioRxiv · Nov 22, 2022Cell Biology

Inflammatory monocytes promote pyogranuloma formation to counteract Yersinia blockade of host defense

D. Sorobetea, R. Matsuda, S. T. Peterson, J. P. Grayczyk, I. Rao, E. Krespan, M. Lanza, C.-A. Assenmacher, D. P. Beiting, E. Radaelli, I. E. Brodsky

This study shows that Yersinia pseudotuberculosis induces pyogranulomas in the murine intestine by blocking phagocytosis, and that monocytes are essential for granuloma formation and immune control.

bioRxiv · Feb 6, 2022 · PreprintMicrobiology

RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signalling

K. Chen, B. Demarco, R. Heilig, S. Ramos, J. Grayczyk, C.-A. Assenmacher, E. Radaelli, L. Joannas, J. Henao-Mejia, I. Brodsky, P. Broz

The paper shows that RIPK1 activates GSDME in neutrophils to promote anti-Yersinia defence through pyroptosis and IL-1β release.

bioRxiv · Jan 20, 2021Immunology

IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii

J. T. Clark, D. A. Christian, J. Gullicksrud, J. A. Perry, J. Park, M. Jacquet, J. C. Tarrant, E. Radaelli, J. Silver, C. A. Hunter

The paper shows IL-33 enhances ILC-mediated resistance to Toxoplasma gondii by promoting IFN-γ production and reducing parasite replication.

bioRxiv · Jan 10, 2021Immunology