Author

I. Epifano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:differential expression· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Stevenson· 2 shared C. Boutell· 2 shared K. Dee· 2 shared Q. Gu· 2 shared S. McFarlane· 2 shared V. Herder· 2 shared A. C. Filipe· 1 shared A. D. S. Filipe· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersMicrobiology

A. Stevenson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Temperature elevation synergises with and enhances the type-I IFN-mediated restriction of MPXV

C. Davis, I. Epifano, K. Dee, S. McFarlane, J. K. Wojtus, B. Brennan, Q. Gu, S. B. Vattipally, L. Tong, L. Orr, A. D. S. Filipe, D. A. Barr, A. Ho, E. C. Thomson, C. Boutell

This study shows that fever enhances the host's type-I IFN response to restrict MPXV replication.

bioRxiv · Sep 29, 2023 · PreprintMicrobiology

Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of the induction of IFN-mediated innate immune defences

V. Herder, K. Dee, J. Wojtus, D. Goldfarb, C. Rozario, Q. Gu, R. Jarrett, I. Epifano, A. Stevenson, S. McFarlane, M. Stewart, A. Szemiel, R. Pinto, A. Masdefiol Garriga, S. Graham, , C. Boutell

This study shows that elevated temperatures inhibit SARS-CoV-2 replication in respiratory epithelium without triggering IFN-mediated immune responses.

bioRxiv · Dec 4, 2020 · PreprintMicrobiology

Respiratory disease in cats associated with human-to-cat transmission of SARS-CoV-2 in the UK

M. J. Hosie, I. Epifano, V. Herder, R. Orton, A. Stevenson, N. Johnson, E. MacDonald, D. Dunbar, M. McDonald, F. Howie, B. Tennant, D. Herrity, A. C. Filipe, D. G. Streicker, B. J. Willett, , COVID-19 Genomics UK Consortium

This study reports two cases of SARS-CoV-2 infection in UK cats linked to human-to-cat transmission, showing mild to severe respiratory disease and genetic variation in the viral genome.

bioRxiv · Sep 23, 2020 · PreprintMicrobiology