R. Pinto

Serum Amyloid A proteins reduce bone mass during mycobacterial infections

This study identifies serum amyloid A proteins as mediators of bone loss during mycobacterial infections through cytokine-driven mechanisms.

Spatiotemporal evaporating droplet dynamics on fomites enhances long term bacterial pathogenesis

This study shows that evaporation-induced bacterial patterns on fomites enhance Salmonella Typhimurium virulence through hyper-proliferation in macrophages and sustained pathogenicity in mice.

COVID-19: A need for new rather than repurposed antiviral drugs.

This paper reviews 29 FDA-approved antiviral compounds for COVID-19 treatment, finds limited clinical efficacy of repurposed drugs, and highlights the need for novel antivirals.

Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of the induction of IFN-mediated innate immune defences

This study shows that elevated temperatures inhibit SARS-CoV-2 replication in respiratory epithelium without triggering IFN-mediated immune responses.

Advax adjuvant formulations promote protective immunity against aerosol Mycobacterium tuberculosis in the absence of deleterious inflammation and reactogenicity

This study evaluates Advax adjuvant formulations for tuberculosis vaccine efficacy, showing they provide strong protection without causing inflammation or reactogenicity.