Author

L. Orr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1

Frequent Co-Authors

C. Boutell· 2 shared Q. Gu· 2 shared A. D. S. Filipe· 1 shared A. Ho· 1 shared A. K. Glaser· 1 shared A. Taggart· 1 shared A. Wickenhagen· 1 shared B. Brennan· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

C. Boutell

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Grayscale 4D Biomaterial Customization at High Resolution and Scale

I. Batalov, J. R. Filteau, R. M. Francis, G. Jaindl, L. Orr, T. L. Rapp, S. Yang, J. A. Filteau, W. Xie, R. C. Bretherton, A. K. Glaser, J. T. C. Liu, K. R. Stevens, C. A. DeForest

This paper introduces GIZMO, a method to create 3D grayscale hydrogel patterns for more realistic tissue engineering.

bioRxiv · Jan 31, 2024 · PreprintBioengineering

Temperature elevation synergises with and enhances the type-I IFN-mediated restriction of MPXV

C. Davis, I. Epifano, K. Dee, S. McFarlane, J. K. Wojtus, B. Brennan, Q. Gu, S. B. Vattipally, L. Tong, L. Orr, A. D. S. Filipe, D. A. Barr, A. Ho, E. C. Thomson, C. Boutell

This study shows that fever enhances the host's type-I IFN response to restrict MPXV replication.

bioRxiv · Sep 29, 2023 · PreprintMicrobiology

Zoonotic avian influenza viruses evade human BTN3A3 restriction

R. M. Pinto, S. Bakshi, S. Lytras, M. K. Zakaria, S. Swingler, J. C. Worrell, V. Herder, M. Varjak, N. Cameron-Ruiz, M. Collados-Rodriguez, M. Varela, A. Wickenhagen, C. Loney, Y. Pei, J. Hughes, , M. Palmarini

This study identifies BTN3A3 as a human restriction factor that inhibits avian influenza viruses but not human IAVs, with resistance linked to specific NP mutations.

bioRxiv · Jun 14, 2022 · PreprintMicrobiology