I. G. Duggin

This study identifies UPEC genes essential for growth and survival during the bladder infection cycle using TraDIS, revealing roles in nutrient utilization, cell envelope stress, and dispersal.

This study identifies RNA-containing extracellular vesicles in Haloferax volcanii, suggesting a potential RNA communication system and linking archaeal EV formation to eukaryotic membrane trafficking origins.

This study identifies a parasitic lifestyle in a DPANN archaeon that causes host cell lysis, suggesting a predatory-like interaction similar to viruses.

This study investigates bacterial multispecies invasion of bladder cells using co-infection models and high-resolution imaging, finding that Gram-negative bacteria are more invasive and exhibit filamentation during dispersal.

This study investigates how bacterial size, shape, surface, and environment affect macrophage engulfment of UPEC filaments, finding that multiple factors contribute to evasion.

This study shows that inducing the bacteriophage PinR in DNA repair-deficient E. coli promotes antibiotic resistance evolution by repressing antioxidative genes and causing ROS bursts.

The paper investigates how DamX localization regulates UPEC filamentation and division during dispersal from host cells, finding that DamX reassembly promotes division and survival.

This study identifies CdrS as a transcriptional regulator essential for cell division in Haloferax volcanii, showing it influences metabolism, protein degradation, and cell division genes.

This study shows that mycobacterial infection induces miR-206, which suppresses neutrophil recruitment via the CXCL12/CXCR4 axis in zebrafish.

This study identifies ymfM, a prophage-encoded gene, as an SOS-inducible cell division inhibitor in E. coli that causes filamentation independently of SulA.

This paper establishes live-cell single-molecule localization microscopy and single-particle tracking in the archaeon Haloferax volcanii by developing a reliable protocol and optimizing fluorescent proteins for imaging.

This study identifies distinct roles for FtsZ1 and FtsZ2 in archaeal cell division, showing FtsZ1 forms the division ring and stabilizes FtsZ2, while FtsZ2 drives constriction.

This study improves growth and morphological plasticity of Haloferax volcanii by supplementing trace elements, revealing the role of CetZ1 in shaping different cell forms.

This study identifies the function of MinD proteins in archaea, showing they oscillate and position motility machinery at cell poles, unlike their bacterial counterparts.