Author

K. de Silva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:zebrafish· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. C. Purdie· 3 shared S. H. Oehlers· 3 shared W. J. Britton· 3 shared K. M. Plain· 2 shared K. Wright· 2 shared A. Figueras· 1 shared A. Romero· 1 shared B. D. Levi· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersImmunology

A. C. Purdie

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Infection-induced miR-126 suppresses tsc1- and cxcl12a-dependent permissive macrophages during mycobacterial infection

K. Wright, K. de Silva, K. M. Plain, A. C. Purdie, W. J. Britton, S. H. Oehlers

This study shows that infection-induced miR-126 suppresses tsc1 and cxcl12a to enhance macrophage function and reduce bacterial burden in zebrafish during mycobacterial infection.

bioRxiv · Oct 7, 2021 · PreprintImmunology

Mycobacterial infection-induced miR-206 inhibits protective neutrophil recruitment via the CXCL12/CXCR4 signalling axis

K. Wright, K. de Silva, K. M. Plain, A. C. Purdie, T. A. Blair, I. G. Duggin, W. J. Britton, S. H. Oehlers

This study shows that mycobacterial infection induces miR-206, which suppresses neutrophil recruitment via the CXCL12/CXCR4 axis in zebrafish.

bioRxiv · Dec 14, 2020Immunology

Single Cell Deconstruction of Muscle Stem Cell Heterogeneity During Aging Reveals Sensitivity to the Neuromuscular Junction

P. J. Ulintz, J. Larouche, M. Mohiuddin, J. Castor Macias, S. J. Kurpiers, W. Liu, J. J. Choi, L. A. Brown, J. F. Markworth, K. de Silva, B. D. Levi, S. D. Merajver, J. V. Chakkalakal, Y. C. Jang, S. V. Brooks, C. A. Aguilar

The paper identifies a neuro-responsive subset of muscle stem cells that support neuromuscular junction integrity during aging and neurodegeneration.

bioRxiv · May 28, 2020Cell Biology

Analysis of mycobacterial infection-induced changes to host lipid metabolism in a zebrafish infection model reveals a conserved role for LDLR in infection susceptibility

M. D. Johansen, E. Hortle, J. A. Kasparian, A. Romero, B. Novoa, A. Figueras, W. J. Britton, K. de Silva, A. C. Purdie, S. H. Oehlers

The paper investigates how mycobacterial infection affects host lipid metabolism in zebrafish, showing that LDLR plays a conserved role in infection susceptibility.

bioRxiv · Jul 23, 2018Immunology